Will I have any rubbing issues if I go from a
225/65/17 to a 255/65/17 on a Dodge caravan
Not sure, but that is a big jump. go to a tire store and ask; they might have a good idea. If you'd rather not risk the drastic increase in tire width and diameter, go to a 235/65R17.
That is over an inch wider and a good bit taller too. Probably a bit optimistic.