I have a 2011 f150 4x4 crew that needs a frame. I also have a 06 4x4 and 04 2x4 crews. will the frame interchange with the 2011?

I doubt it, but you will have to take some measurements. Your 2004 and 2006 F-150's are from the eleventh generation line of F-150's. You 2011 is three years into the twelfth generation. Many new things were introduced mechanically in 2011 so the best you can hope for are predrilled holes not lining up. A good indicator will be checking to see if front suspension parts are interchangeable, which I doubt. A quick visual check of the bolt up location of suspension parts and steering members will give you a definite "no" or "possible" in five minutes.