I am putting a carbed 350 v8 in my 95 s10 and a 700r trans..can i eliminate the computer and all the wires..im putting in all new guages also

You can, as long as you aren't required to pass an emissions test. You'll also be bypassing the anti theft system. If hacking up existing engine harness is too difficult, you can buy hotrod wire harnesses, these can come with 12, 18, 24 circuits or more, depending on your needs. Check out the S10 forums out there, plenty of people have dropped in older carbureted motors in their rides.