Can you run a dodge durango 6 cylinder magnum without the t-stat

Not on a 2004, engine needs to get to operating temp. in order for the closed loop to happen for the computer to be able to adjust air fuel mixture properly, and other sensors to work properly. If you need to run without a thermostat, you may have a plugged radiator, or there are air pockets in the system, or a bad head gasket.

8 hrs. later, thanks tennisshoes, I'll have to remember that engine management terminology. So right back at you!