I have a 85 Chevy c10 4.3 liter v6 with a 350
Transmission I also have a 350 engine will the
350 engine work I want to swap engine
It would work, but you'll have to figure out how to hook it up electrically. I don't know how the 350 is set up for the fuel delivery system, a carburetor or fuel injection. On these years it is a lot easier to do that when you start getting into the '90's. If the 350 is fuel injected then you need the OBD1 computer and wiring harness to go along with it. Your going to need a wiring harness anyway for the 350.
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