misfire in all cylinders

Asked by Aug 14, 2017 at 06:04 PM about the 2007 Toyota Sienna XLE

Question type: Maintenance & Repair

engine check is on and blinks, runs smooth when 1st starting, and for a few
minutes to 10 min., later after accelerating past 50-60 starts to run very
sluggish. diagnostic reads misfire in all 6 cylinders. has been well
225,000 miles. Can the fuel filter be changed? Or do you think it may be
piston/rockers internal timing? This seems to be a common problem in these
vans. If you could please respond with any advice It would greatly appreciate
it.     Thank You Paul.

10 Answers


I would not drive this with CEL blinking. You will ruin your catalytic converters. Fuel filter I believe is in tank with pump. Is this the only codes? P0301 thru P0306? There generally is another or other codes that when fixed, fixes the other 6 misfire codes. Large vacuum leak causing too much fuel to be dumped into engine? Any vacuum hoses disconnected? Not thinking timing. Runs smooth when first started because a cold engine uses more gas. As it heats up it leans out the fuel on a correctly running engine. You have too much fuel being dumped. Manifold gasket leak? P0170 code? 174 code? Unburned fuel is getting to your catalytic converters causing them to potentially be ruined.


Sounds like it's starving for fuel, that will cause random misfires. Check fuel pressure


How long has check engine light been on? Months? years? Thinking bad O2 sensors also. I believe you have 4 on this vehicle 2 upper and 2 lower. I own Toyotas and they need A/F and O2 sensors every 80K or so. I have a 2002 sienna that I keep fresh sensors in. It keeps my money in my pocket instead of in converters. I order and install myself. Denso only.


Irod: I was wondering that myself if it was a P0300? But blinking CEL is always too much fuel.


He said all cylinders not random from his wording. That's why I asked if there was any other codes.

po301 po300,302,303, 304,305,306, and po356, ignition coil F primary. but now it' sounds like clicking and banging inside the head. it's sounds much worse and has barely any power. sounds like something is banging around in the engine. i think its done.


I read several accounts of this and they said one coil made it all better. I would take out and do a visual on coil #6 and inside of plug well. You could also replace harness as this is a possible cause. Check resistance on wire before replacing? I would only replace with a Denso part. I did some research on this last night and several have had your experience.

thank you for the info. and your time. I appreciate it.


When you get this resolved, will you post the fix? Thanks


I just recently had to replace my knock sensor harness on my 02 sienna. I did not drive it before fix. I did go ahead and replace both knock sensors and bypass coolant hose while I had it all apart. From codes, a harness will make all them misfire if in a string with other coils and plugs. I had high resistance in my harness and it was due to being down in V of engine with heat. Yours is most likely heat related also. Might sound crazy but have you tried a junk yard with a low mileage wrecked model that you can pull these parts if you think you have catastrophic failure? It might just fix it and you can buy new after you see what it does...

Your Answer


Looking for a Used Sienna in your area?

CarGurus has 1,112 nationwide Sienna listings starting at $2,995.

Postal Code:

Toyota Sienna Experts

  • #1
  • #2
    Tom Demyan
  • #3
View All

Related Models For Sale

Used Honda Odyssey
13 Great Deals out of 967 listings starting at $2,999
Used Toyota Highlander
26 Great Deals out of 692 listings starting at $838
Used Honda Pilot
15 Great Deals out of 879 listings starting at $2,950
Used Toyota Camry
61 Great Deals out of 1,958 listings starting at $850
Used Dodge Grand Caravan
201 Great Deals out of 11,677 listings starting at $1,850
Used Kia Sedona
11 Great Deals out of 520 listings starting at $3,900
Used Chrysler Town & Country
47 Great Deals out of 640 listings starting at $1,850
Used Nissan Quest
64 listings starting at $2,995
Used Toyota RAV4
54 Great Deals out of 3,252 listings starting at $2,495
Used Toyota 4Runner
6 Great Deals out of 471 listings starting at $5,990
Used Toyota Sequoia
9 Great Deals out of 94 listings starting at $4,500
Used Toyota Corolla
198 Great Deals out of 3,796 listings starting at $1,800
Used Toyota Tacoma
40 Great Deals out of 879 listings starting at $5,990
Used Chrysler Pacifica
9 Great Deals out of 1,480 listings starting at $3,995
Used Honda CR-V
51 Great Deals out of 2,566 listings starting at $1,997

Used Cars For Sale

2017 Toyota Sienna For Sale
538 listings starting at $30,984
2016 Toyota Sienna For Sale
8 Great Deals out of 88 listings starting at $23,999
2015 Toyota Sienna For Sale
69 listings starting at $21,495
2014 Toyota Sienna For Sale
120 listings starting at $16,995

Content submitted by Users is not endorsed by CarGurus, does not express the opinions of CarGurus, and should not be considered reviewed, screened, or approved by CarGurus. Please refer to CarGurus Terms of Use.