Changed spark plugs

Possible causes; Faulty spark plug (s), Faulty ignition coil (s), Clogged or faulty fuel injector (s), Intake air leak, Fuel injectors harness is open or shorted, Fuel Injectors circuit poor electrical connection, Ignition coils harness is open or shorted, Ignition coils circuit poor electrical connection, Insufficient cylinders compression, Incorrect fuel pressure.

or..... one of the spark plug wires came loose from the sparkplug. Been there done that. Is the check engine light lit? If so, what are the code(s)?

It’s probably a bad coil there is a way to test which one bc depending on if you have v6 or v8 there will be 6 for a 6 cylinder and a lot of times your check engine light will stay on and blink meaning deal with it ASAP it’s an easy fix but it could blow your catalytic converter. You can tell which one by seeing which one doesn’t have spark.. watch a video I am a girl and just happen to know a lot about cars from getting used and my 03 trailer blazer has put me through the ringer good thing my friend is a mechanic and works on the side also I replaced 2 so fast in a year and a half get the lifetime warranty bc we just shove any old one in the box if another goes bad and get it for free it’s only like $8-10 bucks more