It may fit but it will not work. No computer to run the trany in a 1972 Ford f100.
Rowefast is right plus you will have problems getting the right flexplate to match the balance of the 72 motor.
Just get a C6 and enjoy the ride my friend
Looking for a Used F-100 in your area?
CarGurus has 4 nationwide F-100 listings and the tools to find you a great deal.
Search Ford F-100 Questions
Ford F-100 Experts